Adam et Max sont deux frères brillants dotés d'un Q.I. de génie. Si Adam se destine à une carrière prometteuse de médecin, Max devient un junkie, vivant même quelques fois dans la rue. Obligé de fuir New York après avoir escroqué des trafiquants de drogue, ce dernier entraîne son frère avec lui en Californie. Un nouveau départ pour les deux frères, un nouveau boulot pour Max, mais le naturel revient au galop et il se met à consommer du crystal meth. Bientôt il perd son emploi et entraîne Adam sur la route de la destruction...

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